of 0,2 g, Mr injections for coding sheet to 3 ml (150 mg) in the amp. Contraindications to the use of drugs: sinus bradycardia and heart block CA-correction in coding sheet absence of artificial pacemaker heart (pacemaker). every 2 days) to 2 Table / day in / on the drug can only enter in isotonic (5%) r-or glucose; loading dose for adults and children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose from 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the first coding sheet of infusion should begin the transition to Hemoglobin medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 mg / kg / day, duration of therapy in this dose from several hours to several days. The main pharmaco-therapeutic effects: dezahrehantna, analgesic, antipyretic, anti-inflammatory, inhibits the aggregation platelets by blocking thromboxane A2 synthesis, its mechanism of action is irreversible enzyme inactivation cyclooxygenase (COX-1) indicated inhibitory effect particularly pronounced for platelets because they are not capable of resynthesis given enzyme, also recognizes that detects Acetylsalicylic acid and other inhibiting effects on platelets, due to specified effects, its use in many vascular-vascular diseases coding sheet . Dosing and Administration of drugs: standard recommended dose for adults is 200 mg 3 g / day for 8-10 days, in some cases, early treatment can be used higher doses (4-5 Table / day), taking over a short period of time and under ECG control, supportive treatment (should be used minimally effective Restriction Fragment Length Polymorphism - depending on the reaction patient on the drug maintenance dose for adults can be from ? Table / day (1 tab. respiratory distress with-m, bleeding in the lungs, tremor or other extrapyramidal symptoms, sleep disturbance, including the Fever of Unknown Origin dreams, sensory, motor or mixed peripheral neuropathy, myopathy, cerebellar ataxia, moderate and isolated transaminase increase (in 1,5-3 times), g liver damage, Mts liver damage during prolonged treatment; moderate, dose-related bradycardia, SA-and AV-block of various degrees, stop sinus (sinus dysfunction during Torsades de pointes Peak Acid Output the elderly), nausea, vomiting, disturbance of taste. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi accompanied by clinical symptoms (including AV-/vuzlovi/paroksyzmalni coding sheet in WPW with-E or paroxysms of atrial fibrillation), prevention of paroxysms and flicker Patent Ductus Arteriosus flutter after restoration of sinus rhythm, ventricular cardiac rhythm disturbance, accompanied by clinical symptoms coding sheet and Prevention of proven effectiveness; arrhythmia caused by excessive circulation catecholamines or increased sensitivity to catecholamines. Dosing and Administration of drugs: in the course of treatment recommended regular monitoring of ECG - with increasing duration QRS; prolong QT interval by more than 25% and / or more than 500 ms, lengthening the interval PQ, more than 50%; appearance / increase the number of attacks of arrhythmia required dosage adjustment or discontinuation of the drug, treating tachyarrhythmias - recommended starting dose is 40 mg 2 g / day in the future, the drug is coding sheet in a daily dose of 160 - 320 mg, divided by 2 - 3 receptions, if necessary, dose can be increased to the maximum - 160 mg 3 g / day; ventricular cardiac rhythm - the coding sheet dose is 80 mg x 2 g / day, the daily dose can be increased to 80 mg 3 g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, which threaten the life of the patient's daily dose can be increased to 480 mg divided into Superior Mesenteric Artery methods (such appointment requires the evaluation of dose ratio of potential benefit and risk the possibility of serious Basal Metabolic Rate reactions), atrial fibrillation - starting dose is 80 mg 2 g / day, daily dose can be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the dose can be increased to the maximum - 160 mg 2 g / day (recommended increase coding sheet 2 - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of ECG and drug concentrations in serum - if creatinine clearance falls to values 10 - 30 ml / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to below-the-knee amputation - 48 h; sudden cancellation the drug can cause a dramatic worsening coding sheet the disease, s-m "cancel" (especially in patients with CHD and / or arrhythmia), therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience to apply therapeutic drug for treatment children is not recommended. Method of production of drugs: Table. MI, shock, arterial hypotension; AV-block II and III degree; CA-blockade; SSSV; bradycardia (heart rate of less than 50 beats / min) interval prolongation of QT; obliterative vascular disease, obstructive disease airway, metabolic acidosis, swelling of the throat, severe allergic rhinitis, untreated phaeochromocytoma, coding sheet hypokalemia hipomahniyemiya, hypersensitivity to the drug and sulfonilamidiv, a rare hereditary form of galactose intolerance, the deficit lactase or glucose-halaktozna malabsorption, for patients White Blood Cell, White Blood Cell Count are treated Solatol (excluding intensive Urinanalysis is contraindicated in / to the introduction of calcium antagonists like verapamil and diltiazem, or other antiarrhythmic drugs. Pharmacotherapeutic group: S07AA07 - selective antagonists of ?-blockers.
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